1db1 Summary

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CRYSTAL STRUCTURE OF THE NUCLEAR RECEPTOR FOR VITAMIN D COMPLEXED TO VITAMIN D

The structure was published by Rochel, N., Wurtz, J.M., Mitschler, A., Klaholz, B., and Moras, D., in 2000 in a paper entitled "The crystal structure of the nuclear receptor for vitamin D bound to its natural ligand." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 1.8 Å and deposited in 1999.

The experimental data on which the structure is based was also deposited.

The PDB entry contains the structure of VITAMIN D NUCLEAR RECEPTOR. This molecule has the UniProt identifier P11473 (VDR_HUMAN)search. The sample contained 259 residues which is < 90% of the natural sequence. Out of 259 residues 250 were observed and are deposited in the PDB.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule is most likely monomeric.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A VITAMIN D NUCLEAR RECEPTOR P11473 (118-427) (VDR_HUMAN)search Homo sapienssearch < 90% 259 96%


This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P11473 (118 - 427) VITAMIN D NUCLEAR RECEPTOR Homo sapiens

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A Nuclear receptor ligand-binding domainsearch Retinoid X Receptorsearch Ligand-binding domain of nuclear hormone receptorsearch

Chain ID Molecular function (GO) Biological process (GO) Cellular component (GO)
A (P11473) sequence-specific DNA binding transcription factor activitysearch steroid hormone receptor activitysearch DNA bindingsearch thyroid hormone receptor activitysearch regulation of transcription, DNA-templatedsearch steroid hormone mediated signaling pathwaysearch nucleussearch

Chain InterPro annotation
A Nuclear hormone receptor, ligand-binding, coresearch Steroid hormone receptorsearch Thyroid hormone receptorsearch Nuclear hormone receptor, ligand-bindingsearch