› 1dab

X-ray diffraction
2.5Å resolution

The Structure of Bordetella Pertussis Virulence Factor P.69 Pertactin

Released:
DOI: 10.2210/pdb1dab/pdb
PDB entry 1dab coloured by chain, front view.
PDB entry 1dab coloured by chain, side view.
PDB entry 1dab coloured by chain, top view.
Source organism: Bordetella pertussis
Primary publication:
Structure of Bordetella pertussis virulence factor P.69 pertactin.
Emsley P, Charles IG, Fairweather NF, Isaacs NW
Nature 381 90-2 (1996)
PMID: 8609998

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo hexamer
Assembly name:
PDBe Complex ID:
PDB-CPX-146894 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Outer membrane protein P.69 Chain: A
Molecule details ›
Chain: A
Length: 539 amino acids
Theoretical weight: 54.63 KDa
Source organism: Bordetella pertussis
Expression system: Escherichia coli
UniProt:
  • Canonical: P14283 (Residues: 35-573; Coverage: 62%)
Gene names: BP1054, omp69A, prn
Sequence domains: Pertactin
Structure domains: Pectate Lyase C-like

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SRS BEAMLINE PX9.6
Spacegroup: P6322
Unit cell:
a: 176.199Å b: 176.199Å c: 104.688Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.251 0.25 0.276
Expression system: Escherichia coli

Quick links

Citations

48 review citations

Molecular pathogenesis, epidemiology, and clinical manifestations of respiratory infections due to Bordetella pertussis and other Bordetella subspecies.
Mattoo et al. (2005)
47 more

32 mentions without citation

Type V protein secretion pathway: the autotransporter story.
Henderson et al. (2004)
31 more