spacer CRYSTAL STRUCTURE OF E. COLI DNA TOPOISOMERASE III
SCOP: Structural Classification of Proteins
Domain 43248search
SCCS e.10.1.1search
Description 1d6m A:
Comments
Polymers A
UniProt P14294
Hierarchy
Class Multi-domain proteins (alpha and beta) search
Fold Prokaryotic type I DNA topoisomerase search
4 domains: (1) Toprim alpha/beta; (2&4) "winged helix"-like; (3) barrel: n=6, S=8
Superfamily Prokaryotic type I DNA topoisomerase search
duplication: the protein chain passing through the domains 2-4 makes two structural repeats
The active site is formed by the toprim and "winged helix" domains (domains 1 and 4); these two domains are also found in the type II topoisomerase (DNA gyrase A) and in the alpha subunit of topoisomerase IV
Family Prokaryotic type I DNA topoisomerase search
domain 4 contains the catalytic tyrosine residue
Protein DNA topoisomerase III search
 
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