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CHALCONE SYNTHASE (H303Q MUTANT)

X-ray diffraction
2Å resolution
PDB entry 1d6i coloured by chain, front view.
PDB entry 1d6i coloured by chain, side view.
PDB entry 1d6i coloured by chain, top view.
Source organism: Medicago sativa
Assemblies composition:
homo tetramer
homo dimer (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1
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Assembly Name: Chalcone synthase 2
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Multimeric state: homo tetramer
Accessible surface area: 59109.36 Å2
Buried surface area: 7070.88 Å2
Dissociation area: 157.88 Å2
Dissociation energy (ΔGdiss): -27.54 kcal/mol
Dissociation entropy (TΔSdiss): 28.11 kcal/mol
Symmetry number: 2
PDBe Complex ID: PDB-CPX-151629
Assembly 2 (preferred)
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Assembly Name: Chalcone synthase 2
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Multimeric state: homo dimer
Accessible surface area: 26619.84 Å2
Buried surface area: 6483.98 Å2
Dissociation area: 3,107.31 Å2
Dissociation energy (ΔGdiss): 30.75 kcal/mol
Dissociation entropy (TΔSdiss): 14.62 kcal/mol
Symmetry number: 2
PDBe Complex ID: PDB-CPX-151628

Macromolecules

Chalcone synthase 2
Chains: A, B
Length: 388 amino acids
Theoretical weight: 42.65 KDa
Source organism: Medicago sativa
Expression system: Escherichia coli
UniProt:
  • Canonical: P30074 (Residues: 2-389; Coverage: 100%)
Gene name: CHS2
Pfam:
InterPro:
CATH: Peroxisomal Thiolase; Chain A, domain 1
SCOP: Chalcone synthase-like
Chalcone synthase 2 in PDB entry 1d6i, assembly 2, front view.
Chalcone synthase 2 in PDB entry 1d6i, assembly 2, side view.
Chalcone synthase 2 in PDB entry 1d6i, assembly 2, top view.
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