› › Structure analysis

CRYSTAL STRUCTURE OF THE XLP PROTEIN SAP IN COMPLEX WITH SLAM PHOSPHOPEPTIDE

X-ray diffraction
1.8Å resolution
PDB entry 1d4w coloured by chain, front view.
PDB entry 1d4w coloured by chain, side view.
PDB entry 1d4w coloured by chain, top view.
Source organism: Homo sapiens
Assembly composition:
hetero dimer (preferred)
Entry contents: 2 distinct polypeptide molecules

Quick links

Assemblies

Assembly 1 (preferred)
Download    3D Visualisation
Assembly Name: Signaling lymphocytic activation molecule and SH2 domain-containing protein 1A
hide full assembly name
Multimeric state: hetero dimer
Accessible surface area: 6240.28 Å2
Buried surface area: 1733.59 Å2
Dissociation area: 866.8 Å2
Dissociation energy (ΔGdiss): 13.66 kcal/mol
Dissociation entropy (TΔSdiss): 7.79 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-130108
Assembly 2
Download    3D Visualisation
Assembly Name: Signaling lymphocytic activation molecule and SH2 domain-containing protein 1A
hide full assembly name
Multimeric state: hetero dimer
Accessible surface area: 5920.32 Å2
Buried surface area: 1799.75 Å2
Dissociation area: 899.88 Å2
Dissociation energy (ΔGdiss): 15.09 kcal/mol
Dissociation entropy (TΔSdiss): 7.81 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-130108

Macromolecules

SH2 domain-containing protein 1A
Chains: A, B
Length: 104 amino acids
Theoretical weight: 11.7 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: O60880 (Residues: 1-104; Coverage: 81%)
Gene names: DSHP, SAP, SH2D1A
Pfam: SH2 domain
InterPro:
CATH: SH2 domain
SCOP: SH2 domain
SH2 domain-containing protein 1A in PDB entry 1d4w, assembly 1, front view.
SH2 domain-containing protein 1A in PDB entry 1d4w, assembly 1, side view.
SH2 domain-containing protein 1A in PDB entry 1d4w, assembly 1, top view.
Molecule details ›

Search similar proteins

Signaling lymphocytic activation molecule
Chains: C, D
Length: 11 amino acids
Theoretical weight: 1.36 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: Q13291 (Residues: 276-286; Coverage: 4%)
Gene names: SLAM, SLAMF1
Signaling lymphocytic activation molecule in PDB entry 1d4w, assembly 1, front view.
Signaling lymphocytic activation molecule in PDB entry 1d4w, assembly 1, side view.
Signaling lymphocytic activation molecule in PDB entry 1d4w, assembly 1, top view.
Molecule details ›

Search similar proteins

Quick links