1d4t Summary

pdbe.org/1d4t
spacer

CRYSTAL STRUCTURE OF THE XLP PROTEIN SAP IN COMPLEX WITH A SLAM PEPTIDE

The structure was published by Poy, F., Yaffe, M.B., Sayos, J., et al., Cantley, L.C., Terhorst, C., and Eck, M.J., in 1999 in a paper entitled "Crystal structures of the XLP protein SAP reveal a class of SH2 domains with extended, phosphotyrosine-independent sequence recognition." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 1.1 Å and deposited in 1999.

The experimental data on which the structure is based was also deposited.

This PDB entry contains a complex of 2 biomacromolecules, namely T CELL SIGNAL TRANSDUCTION MOLECULE SAP and SIGNALING LYMPHOCYTIC ACTIVATION MOLECULE.

The molecule most likely forms heterodimers.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A T CELL SIGNAL TRANSDUCTION MOLECULE SAP O60880 (1-104) (SH21A_HUMAN)search Homo sapienssearch 100% 104 100%
B SIGNALING LYMPHOCYTIC ACTIVATION MOLECULE Q13291 (276-286) (SLAF1_HUMAN)search Homo sapienssearch < 90% 11 100%


This entry contains 2 unique UniProt proteins:

UniProt accession Name Organism PDB
O60880 (1 - 104) T CELL SIGNAL TRANSDUCTION MOLECULE SAP Homo sapiens
Q13291 (276 - 286) SIGNALING LYMPHOCYTIC ACTIVATION MOLECULE

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A (O60880) SH2 domainsearch SHC Adaptor Proteinsearch PF00017: SH2 domainsearch
B
Chain InterPro annotation
A SH2 domainsearch
B