HUMAN DIHYDROOROTATE DEHYDROGENASE COMPLEXED WITH BREQUINAR ANALOG
The structure was published by Liu, S., Neidhardt, E.A., Grossman, T.H., Ocain, T., and Clardy, J., in 2000 in a paper entitled "Structures of human dihydroorotate dehydrogenase in complex with antiproliferative agents." (abstract).
This crystal structure was determined using X-ray diffraction at a resolution of 1.6 Å and deposited in 1999.
The experimental data on which the structure is based was also deposited.
The PDB entry contains the structure of DIHYDROOROTATE DEHYDROGENASE. This molecule has the UniProt identifier Q02127 (PYRD_HUMAN). The sample contained 367 residues which is 93% of the natural sequence. Out of 367 residues 360 were observed and are deposited in the PDB.
It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.
The molecule is most likely monomeric.
The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):
This entry contains 1 unique UniProt protein: