1d0s Summary

pdbe.org/1d0s
spacer

CRYSTAL STRUCTURE OF NICOTINATE MONONUCLEOTIDE : 5,6-DIMETHYLBENZIMIDAZOLE PHOSPHORIBOSYLTRANSFERASE (COBT) FROM SALMONELLA TYPHIMURIUM COMPLEXED WITH 5, 6-DIMETHYLBENZIMIDAZOLE

The structure was published by Cheong, C.G., Escalante-Semerena, J.C., and Rayment, I., in 1999 in a paper entitled "The three-dimensional structures of nicotinate mononucleotide:5,6- dimethylbenzimidazole phosphoribosyltransferase (CobT) from Salmonella typhimurium complexed with 5,6-dimethybenzimidazole and its reaction products determined to 1.9 A resolution." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 1.9 Å and deposited in 1999.

The experimental data on which the structure is based was also deposited.

The PDB entry contains the structure of NICOTINATE MONONUCLEOTIDE:5,6-DIMETHYLBENZIMIDAZOLE PHOSPHORIBOSYLTRANSFERASE. This molecule has the UniProt identifier Q05603 (COBT_SALTY)search. The sample contained 356 residues which is 100% of the natural sequence. Out of 356 residues 339 were observed and are deposited in the PDB.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule most likely forms homodimers.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A NICOTINATE MONONUCLEOTIDE:5,6-DIMETHYLBENZIMIDAZOLE PHOSPHORIBOSYLTRANSFERASE Q05603 (1-356) (COBT_SALTY)search Salmonella enterica subsp. enterica serovar Typhimurium str. LT2search 100% 356 97%


This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
Q05603 (1 - 356) NICOTINATE MONONUCLEOTIDE:5,6-DIMETHYLBENZIMIDAZOLE PHOSPHORIBOSYLTRANSFERASE Salmonella enterica subsp. enterica serovar Typhimurium

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A (Q05603) Nicotinate mononucleotide:5,6-dimethylbenzimidazole phosphoribosyltransferase (CobT)search 5,6-Dimethylbenzimidazole Phosphoribosyltransferase; Chain: A; domain 1search, Rossmann foldsearch PF02277: Phosphoribosyltransferasesearch

Chain ID Molecular function (GO) Biological process (GO)
A (Q05603) nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activitysearch transferase activitysearch transferase activity, transferring glycosyl groupssearch cobalamin-transporting ATPase activitysearch cobalamin biosynthetic processsearch cobalamin transportsearch vitamin transmembrane transportsearch nucleoside biosynthetic processsearch

Chain InterPro annotation
A Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-likesearch Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, prokaryoticsearch Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, N-terminalsearch