1ctt Summary

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TRANSITION-STATE SELECTIVITY FOR A SINGLE OH GROUP DURING CATALYSIS BY CYTIDINE DEAMINASE

The structure was published by Xiang, S., Short, S.A., Wolfenden, R., and Carter Jr., C.W., in 1995 in a paper entitled "Transition-state selectivity for a single hydroxyl group during catalysis by cytidine deaminase." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 2.2 Å and deposited in 1995.

The experimental data on which the structure is based was also deposited.

The PDB entry contains the structure of CYTIDINE DEAMINASE. This molecule has the UniProt identifier P0ABF6 (CDD_ECOLI)search. The sample contained 294 residues which is 100% of the natural sequence. Out of 294 residues 294 were observed and are deposited in the PDB.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule most likely forms homodimers.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A CYTIDINE DEAMINASE P0ABF6 (1-294) (CDD_ECOLI)search Escherichia coli K-12search 100% 294 100%


This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P0ABF6 (1 - 294) CYTIDINE DEAMINASE Escherichia coli

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A (P0ABF6) Cytidine deaminasesearch Cytidine Deaminase, domain 2search PF00383: Cytidine and deoxycytidylate deaminase zinc-binding regionsearch, PF08211: Cytidine and deoxycytidylate deaminase zinc-binding regionsearch

Chain ID Molecular function (GO) Biological process (GO) Cellular component (GO)
A (P0ABF6) zinc ion bindingsearch cytidine deaminase activitysearch hydrolase activitysearch catalytic activitysearch pyrimidine nucleoside bindingsearch metal ion bindingsearch identical protein bindingsearch deoxycytidine deaminase activitysearch cytidine deaminationsearch nucleobase-containing small molecule interconversionsearch deoxycytidine catabolic processsearch cytosolsearch

Chain InterPro annotation
A CMP/dCMP deaminase, zinc-bindingsearch Cytidine deaminase, homodimericsearch Cytidine/deoxycytidylate deaminase, zinc-binding domainsearch APOBEC/CMP deaminase, zinc-bindingsearch Cytidine deaminase-likesearch Cytidine deaminase, bacteriasearch