1csz Summary

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SYK TYROSINE KINASE C-TERMINAL SH2 DOMAIN COMPLEXED WITH A PHOSPHOPEPTIDEFROM THE GAMMA CHAIN OF THE HIGH AFFINITY IMMUNOGLOBIN G RECEPTOR, NMR

The structure was published by Narula, S.S., Yuan, R.W., Adams, S.E., et al., Zoller, M.J., Karas, J.L., and Dalgarno, D.C., in 1995 in a paper entitled "Solution structure of the C-terminal SH2 domain of the human tyrosine kinase Syk complexed with a phosphotyrosine pentapeptide." (abstract).

The structure was determined using NMR spectroscopy and deposited in 1995.

The experimental data on which the structure is based was not deposited.

This PDB entry contains a complex of 2 biomacromolecules, namely SYK PROTEIN TYROSINE KINASE and ACETYL-THR-PTR-GLU-THR-LEU-NH2.

The molecule most likely forms heterodimers.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A SYK PROTEIN TYROSINE KINASE P43405 (163-265) (KSYK_HUMAN)search Homo sapienssearch 100% 112 100%


This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P43405 (163 - 265) SYK PROTEIN TYROSINE KINASE Homo sapiens

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A (P43405) SH2 domainsearch SHC Adaptor Proteinsearch PF00017: SH2 domainsearch
Chain InterPro annotation
A SH2 domainsearch