1coo Summary



The structure was published by Jeon, Y.H., Negishi, T., Shirakawa, M., et al., Fujita, N., Ishihama, A., and Kyogoku, Y., in 1995 in a paper entitled "Solution structure of the activator contact domain of the RNA polymerase alpha subunit." (abstract).

The structure was determined using NMR spectroscopy and deposited in 1995.

The experimental data on which the structure is based was not deposited.

The PDB entry contains the structure of RNA POLYMERASE ALPHA SUBUNIT. This molecule has the UniProt identifier P0A7Z4 (RPOA_ECOLI)search. The sample contained 98 residues which is < 90% of the natural sequence. Out of 98 residues 81 were observed and are deposited in the PDB.

The molecule is most likely monomeric.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):

Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A RNA POLYMERASE ALPHA SUBUNIT P0A7Z4 (233-329) (RPOA_ECOLI)search Escherichia coli K-12search 100% 98 82%

This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P0A7Z4 (233 - 329) RNA POLYMERASE ALPHA SUBUNIT Escherichia coli K-12

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A (P0A7Z4) C-terminal domain of RNA polymerase alpha subunitsearch 5' to 3' exonuclease, C-terminal subdomainsearch PF03118: Bacterial RNA polymerase, alpha chain C terminal domainsearch

Chain ID Molecular function (GO) Biological process (GO)
A (P0A7Z4) DNA-directed RNA polymerase activitysearch DNA bindingsearch transcription, DNA-templatedsearch

Chain InterPro annotation
A RNA polymerase, alpha subunit, C-terminalsearch