› 1cki

X-ray diffraction
2.3Å resolution

RECOMBINANT CASEIN KINASE I DELTA TRUNCATION MUTANT CONTAINING RESIDUES 1-317

Released:
DOI: 10.2210/pdb1cki/pdb
PDB entry 1cki coloured by chain, front view.
PDB entry 1cki coloured by chain, side view.
PDB entry 1cki coloured by chain, top view.
Source organism: Rattus norvegicus
Primary publication:
Three-dimensional structure of mammalian casein kinase I: molecular basis for phosphate recognition.
Longenecker KL, Roach PJ, Hurley TD
J Mol Biol 257 618-31 (1996)
PMID: 8648628

Function and Biology Details

Reactions catalysed: 
ATP + a protein = ADP + a phosphoprotein
ATP + [tau protein] = ADP + [tau protein] phosphate
Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-170352 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Casein kinase I isoform delta Chains: A, B
Molecule details ›
Chains: A, B
Length: 317 amino acids
Theoretical weight: 37 KDa
Source organism: Rattus norvegicus
Expression system: Escherichia coli
UniProt:
  • Canonical: Q06486 (Residues: 1-317; Coverage: 76%)
Gene names: Csnk1d, Hckid
Sequence domains: Protein kinase domain
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: P212121
Unit cell:
a: 106.84Å b: 115.47Å c: 60.6Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.193 0.193 0.279
Expression system: Escherichia coli

Quick links

Citations

18 review citations

Regulation of protein kinases; controlling activity through activation segment conformation.
Nolen et al. (2004)
17 more

11 mentions without citation

Overview of protein structural and functional folds.
Sun et al. (2004)
10 more