1cgk Summary



The structure was published by Ferrer, J.L., Jez, J.M., Bowman, M.E., Dixon, R.A., and Noel, J.P., in 1999 in a paper entitled "Structure of chalcone synthase and the molecular basis of plant polyketide biosynthesis." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 1.84 Å and deposited in 1999.

The experimental data on which the structure is based was also deposited.

The PDB entry contains the structure of PROTEIN (CHALCONE SYNTHASE). This molecule has the UniProt identifier P30074 (CHS2_MEDSA)search. The sample contained 389 residues which is 100% of the natural sequence. Out of 389 residues 387 were observed and are deposited in the PDB.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule most likely forms homodimers.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):

Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A PROTEIN (CHALCONE SYNTHASE) P30074 (1-389) (CHS2_MEDSA)search Medicago sativasearch 99% 389 99%

This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P30074 (1 - 389) PROTEIN (CHALCONE SYNTHASE) Medicago sativa

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A (P30074) Chalcone synthase-likesearch Peroxisomal Thiolase; Chain A, domain 1search PF00195: Chalcone and stilbene synthases, N-terminal domainsearch, PF02797: Chalcone and stilbene synthases, C-terminal domainsearch

Chain ID Biological process (GO) Molecular function (GO)
A (P30074) flavonoid biosynthetic processsearch biosynthetic processsearch metabolic processsearch chalcone biosynthetic processsearch naringenin-chalcone synthase activitysearch transferase activity, transferring acyl groups other than amino-acyl groupssearch transferase activity, transferring acyl groupssearch catalytic activitysearch transferase activitysearch

Chain InterPro annotation
A Chalcone/stilbene synthase, N-terminalsearch Polyketide synthase, type IIIsearch Chalcone/stilbene synthase, C-terminalsearch Thiolase-like, subgroupsearch Thiolase-likesearch Chalcone/stilbene synthase, active sitesearch