STRUCTURE OF HUMAN 5'-DEOXY-5'-METHYLTHIOADENOSINE PHOSPHORYLASE COMPLEXED WITH 5'-DEOXY-5'-METHYLTHIOADENOSINE AND SULFATE AT 1.7 A RESOLUTION
The structure was published by Appleby, T.C., Erion, M.D., and Ealick, S.E., in 1999 in a paper entitled "The structure of human 5'-deoxy-5'-methylthioadenosine phosphorylase at 1.7 A resolution provides insights into substrate binding and catalysis." (abstract).
This crystal structure was determined using X-ray diffraction at a resolution of 1.7 Å and deposited in 1999.
The experimental data on which the structure is based was not deposited.
The PDB entry contains the structure of PROTEIN (5'-DEOXY-5'-METHYLTHIOADENOSINE PHOSPHORYLASE). This molecule has the UniProt identifier Q13126 (MTAP_HUMAN). The sample contained 283 residues which is 100% of the natural sequence. Out of 283 residues 268 were observed and are deposited in the PDB.
It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.
The molecule most likely forms homotrimers.
The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):
This entry contains 1 unique UniProt protein: