1cfp Summary

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S100B (S100BETA) NMR DATA WAS COLLECTED FROM A SAMPLE OF CALCIUM FREE PROTEIN AT PH 6.3 AND A TEMPERATURE OF 311 K AND 1.7-6.9 MM CONCENTRATION, 25 STRUCTURES

The structure was published by Kilby, P.M., Van Eldik, L.J., and Roberts, G.C., in 1996 in a paper entitled "The solution structure of the bovine S100B protein dimer in the calcium-free state." (abstract).

The structure was determined using NMR spectroscopy and deposited in 1996.

The experimental data on which the structure is based was also deposited.

This PDB entry contains multiple copies of the structure of S100B.

The molecule most likely forms homodimers.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A S100B P02638 (1-92) (S100B_BOVIN)search Bos taurussearch 96% 92 100%
B S100B P02638 (1-92) (S100B_BOVIN)search Bos taurussearch 96% 92 100%


This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P02638 (1 - 92) S100B Bos taurus

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A, B (P02638) S100 proteinssearch EF-handsearch PF00036: EF handsearch, PF01023: S-100/ICaBP type calcium binding domainsearch

Chain ID Cellular component (GO) Molecular function (GO) Biological process (GO)
A, B (P02638) intracellular membrane-bounded organellesearch cytoplasmsearch nucleussearch perinuclear region of cytoplasmsearch neuronal cell bodysearch rufflesearch calcium ion bindingsearch S100 protein bindingsearch protein bindingsearch zinc ion bindingsearch kinase inhibitor activitysearch protein homodimerization activitysearch identical protein bindingsearch calcium-dependent protein bindingsearch tau protein bindingsearch RAGE receptor bindingsearch metal ion bindingsearch negative regulation of phosphorylationsearch regulation of neuronal synaptic plasticitysearch axonogenesissearch positive regulation of I-kappaB kinase/NF-kappaB signalingsearch memorysearch astrocyte activationsearch learning or memorysearch regulation of translationsearch positive regulation of complement activationsearch phosphorylationsearch

Chain InterPro annotation
A, B S100/Calbindin-D9k, conserved sitesearch EF-hand domainsearch EF-hand domain pairsearch S100/CaBP-9k-type, calcium binding, subdomainsearch EF-Hand 1, calcium-binding sitesearch Protein S100-Bsearch