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EBI PDBe PDBeView

PDBe Entry: 1c3r view

CRYSTAL STRUCTURE OF AN HDAC HOMOLOG COMPLEXED WITH TRICHOSTATIN A
Summary
Header LYASEsearch
Method X-RAY DIFFRACTION
Experiment Resolution: 2.0 Å, R-factor: 22.4%, Free R-factor: 25.8%, Spacegroup: P 21 21 21
Released 15/09/1999, deposition: 28/07/1999, last revision: 24/02/2009
Authors Finnin, M.S.search; Donigian, J.R.search; Pavletich, N.P.search
Primary citation Structures of a histone deacetylase homologue bound to the TSA and SAHA inhibitors.
NATUREsearch vol:401, pag:188-193 (1999) [PubMed ID 10490031 ]search
Keywords ALPHA/BETA FOLDsearch, HYDROXAMIC ACIDsearch, CHARGE-RELAY SYSTEMsearch, PENTA-COORDINATED ZINCsearch, LYASEsearch
Organism Aquifex aeolicus 63363search(A B)
UniProt Acetoin utilization protein O67135search (A B)
Solvent A, B
Related entries 1c3p, 1c3s
Polymers
Id Name Type UniProt Residues Observed
A, B HDLP (HISTONE DEACETYLASE-LIKE PROTEIN) Protein O67135 (O67135_AQUAE)search
 375 99%
Heterogens
Id Name Ligands
A, B ZINC ION ZN search
A, B TRICHOSTATIN A TSN search
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