› 1bz8

X-ray diffraction
2Å resolution

TRANSTHYRETIN (DEL VAL122)

Released:
DOI: 10.2210/pdb1bz8/pdb
PDB entry 1bz8 coloured by chain, front view.
PDB entry 1bz8 coloured by chain, side view.
PDB entry 1bz8 coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Schormann N, Uemichi T, Benson MD

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-136168 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Transthyretin Chains: A, B
Molecule details ›
Chains: A, B
Length: 126 amino acids
Theoretical weight: 13.68 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P02766 (Residues: 21-147; Coverage: 99%)
Gene names: PALB, TTR
Sequence domains: HIUase/Transthyretin family
Structure domains: Transthyretin/hydroxyisourate hydrolase domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU200
Spacegroup: P21212
Unit cell:
a: 43.33Å b: 86.75Å c: 65.05Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.193 0.193 0.277
Expression system: Escherichia coli

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