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PDBe Entry: 1bws view

CRYSTAL STRUCTURE OF GDP-4-KETO-6-DEOXY-D-MANNOSE EPIMERASE/REDUCTASE FROM ESCHERICHIA COLI A KEY ENZYME IN THE BIOSYNTHESIS OF GDP-L-FUCOSE
Summary
Header OXIDOREDUCTASEsearch
Method X-RAY DIFFRACTION
Experiment Resolution: 2.2 Å, Spacegroup: P 32 2 1
Released 13/01/1999, deposition: 25/09/1998, last revision: 24/02/2009
Authors Rizzi, M.search; Tonetti, M.search; Flora, A.D.search; Bolognesi, M.search
Primary citation GDP-4-keto-6-deoxy-D-mannose epimerase/reductase from Escherichia coli, a key enzyme in the biosynthesis of GDP-L-fucose, displays the structural characteristics of the RED protein homology superfamily.
STRUCTUREsearch vol:6, pag:1453-1465 (1998) [PubMed ID 9817848 ]search
Keywords EPIMERASE/REDUCTASEsearch, GDP-L-FUCOSE BIOSYNTHESISsearch, OXIDOREDUCTASEsearch
EC 1.1.1.271 ExPASy BRENDA search (A)
Organism Escherichia coli 562search(A)
UniProt GDP-L-fucose synthetase (EC 1.1.1.271) (GDP-4-keto-6-deoxy-D-mannose-3,5-epimerase-4-reductase) P32055search (A)
Solvent A
Polymers
Id Name Type UniProt Residues Observed
A PROTEIN (GDP-4-KETO-6-DEOXY-D-MANNOSE EPIMERASE/REDUCTASE) Protein P32055 (FCL_ECOLI)search
 321 97%
Heterogens
Id Name Ligands
A NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE NDP search
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