1bwp Summary

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PROBING THE SUBSTRATE SPECIFICITY OF THE INTRACELLULAR BRAIN PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE

The structure was published by Ho, Y.S., Sheffield, P.J., Masuyama, J., et al., Inoue, K., Derewenda, U., and Derewenda, Z.S., in 1999 in a paper entitled "Probing the Substrate Specificity of the Intracellular Brain Platelet-Activating Factor Acetylhydrolase" (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 2.1 Å and deposited in 1998.

The experimental data on which the structure is based was not deposited.

The PDB entry contains the structure of PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE. This molecule has the UniProt identifier Q29460 (PA1B3_BOVIN)search. The sample contained 233 residues which is 100% of the natural sequence. Out of 233 residues 212 were observed and are deposited in the PDB.

The molecule most likely forms homodimers.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE Q29460 (1-232) (PA1B3_BOVIN)search Bos taurussearch 100% 233 90%


This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
Q29460 (1 - 232) PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE Bos taurus

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A (Q29460) Acetylhydrolasesearch Rossmann foldsearch PF13472: GDSL-like Lipase/Acylhydrolase familysearch

Chain ID Molecular function (GO) Cellular component (GO) Biological process (GO)
A (Q29460) 1-alkyl-2-acetylglycerophosphocholine esterase activitysearch platelet-activating factor acetyltransferase activitysearch hydrolase activitysearch cytoplasmsearch extracellular vesicular exosomesearch membranesearch spermatogenesissearch lipid catabolic processsearch brain developmentsearch lipid metabolic processsearch

Chain InterPro annotation
A SGNH hydrolase-type esterase domainsearch