Function and Biology Details
Reaction catalysed:
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domains:
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-150319 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Cyclin-dependent kinase 2
Molecule details ›
Chain: A
Length: 298 amino acids
Theoretical weight: 33.98 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
Sequence domains: Protein kinase domain
Structure domains:
Length: 298 amino acids
Theoretical weight: 33.98 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
- Canonical:
P24941 (Residues: 1-298; Coverage: 100%)
Sequence domains: Protein kinase domain
Structure domains:
Cyclin-dependent kinases regulatory subunit 1
Molecule details ›
Chain: B
Length: 79 amino acids
Theoretical weight: 9.68 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: Cyclin-dependent kinase regulatory subunit
Structure domains: Cyclin-dependent kinase, regulatory subunit
Length: 79 amino acids
Theoretical weight: 9.68 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical: P61024 (Residues: 1-79; Coverage: 100%)
Sequence domains: Cyclin-dependent kinase regulatory subunit
Structure domains: Cyclin-dependent kinase, regulatory subunit
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
SIEMENS
Spacegroup:
P21
Expression systems:
- Trichoplusia ni
- Escherichia coli
