1btg Summary

pdbe.org/1btg
spacer

CRYSTAL STRUCTURE OF BETA NERVE GROWTH FACTOR AT 2.5 A RESOLUTION IN C2 SPACE GROUP WITH ZN IONS BOUND

There is a Quite Interesting Protein Structure article for this entry.

The structure was published by Holland, D.R., Cousens, L.S., Meng, W., and Matthews, B.W., in 1994 in a paper entitled "Nerve growth factor in different crystal forms displays structural flexibility and reveals zinc binding sites." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 2.5 Å and deposited in 1995.

The experimental data on which the structure is based was not deposited.

This PDB entry contains multiple copies of the structure of BETA NERVE GROWTH FACTOR.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule has more than one probable quaternary state observed. For more details see the quaternary structure page.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A BETA NERVE GROWTH FACTOR P01139 (130-239) (NGF_MOUSE)search Mus musculussearch 100% 110 99%
B BETA NERVE GROWTH FACTOR P01139 (130-239) (NGF_MOUSE)search Mus musculussearch 100% 110 99%
C BETA NERVE GROWTH FACTOR P01139 (130-239) (NGF_MOUSE)search Mus musculussearch 100% 110 99%


This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P01139 (130 - 239) BETA NERVE GROWTH FACTOR Mus musculus

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A, B, C (P01139) Neurotrophinsearch Cystine-knot cytokinessearch PF00243: Nerve growth factor familysearch

Chain ID Molecular function (GO)
A, B, C (P01139) receptor bindingsearch

Chain InterPro annotation
A, B, C Nerve growth factor-relatedsearch Nerve growth factor conserved sitesearch Nerve growth factor-likesearch Nerve growth factor, beta subunitsearch Cystine-knot cytokinesearch