Function and Biology

CRYSTAL STRUCTURE OF BETA NERVE GROWTH FACTOR AT 2.5 A RESOLUTION IN C2 SPACE GROUP WITH ZN IONS BOUND

Source organism: Mus musculus
Biochemical function: signaling receptor binding
Biological process: not assigned
Cellular component: not assigned

GO terms

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Sequence family

Pfam Protein family (Pfam)
PF00243
Domain description: Nerve growth factor family
Occurring in:
  1. Beta-nerve growth factor
The deposited structure of PDB entry 1btg contains 3 copies of Pfam domain PF00243 (Nerve growth factor family) in Beta-nerve growth factor. Showing 1 copy in chain B.

InterPro InterPro annotations
IPR002072
Domain description: Nerve growth factor-related
Occurring in:
  1. Beta-nerve growth factor
IPR020425
Domain description: Nerve growth factor, beta subunit
Occurring in:
  1. Beta-nerve growth factor
IPR029034
Domain description: Cystine-knot cytokine
Occurring in:
  1. Beta-nerve growth factor
IPR019846
Domain description: Nerve growth factor conserved site
Occurring in:
  1. Beta-nerve growth factor
IPR020408
Domain description: Nerve growth factor-like
Occurring in:
  1. Beta-nerve growth factor

Structure domain

CATH CATH domain
2.10.90.10
Class: Mainly Beta
Architecture: Ribbon
Topology: Cystine Knot Cytokines, subunit B
Homology: Cystine-knot cytokines
Occurring in:
  1. Beta-nerve growth factor
The deposited structure of PDB entry 1btg contains 3 copies of CATH domain 2.10.90.10 (Cystine Knot Cytokines, subunit B) in Beta-nerve growth factor. Showing 1 copy in chain B.
SCOP SCOP annotation
57520
Class: Small proteins
Fold: Cystine-knot cytokines
Superfamily: Cystine-knot cytokines
Occurring in:
  1. Beta-nerve growth factor
The deposited structure of PDB entry 1btg contains 3 copies of SCOP domain 57520 (Neurotrophin) in Beta-nerve growth factor. Showing 1 copy in chain B.