1brw Summary



The structure was published by Pugmire, M.J. and Ealick, S.E., in 1998 in a paper entitled "The crystal structure of pyrimidine nucleoside phosphorylase in a closed conformation." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 2.1 Å and deposited in 1998.

The experimental data on which the structure is based was also deposited.

This PDB entry contains multiple copies of the structure of PROTEIN (PYRIMIDINE NUCLEOSIDE PHOSPHORYLASE).

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule most likely forms homodimers.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):

Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A PROTEIN (PYRIMIDINE NUCLEOSIDE PHOSPHORYLASE) P77836 (1-432) (PDP_GEOSE)search Geobacillus stearothermophilussearch 100% 433 100%
B PROTEIN (PYRIMIDINE NUCLEOSIDE PHOSPHORYLASE) P77836 (1-432) (PDP_GEOSE)search Geobacillus stearothermophilussearch 100% 433 100%

This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P77836 (1 - 432) PROTEIN (PYRIMIDINE NUCLEOSIDE PHOSPHORYLASE) Geobacillus stearothermophilus

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A, B (P77836) Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domainsearch, Nucleoside phosphorylase/phosphoribosyltransferase catalytic domainsearch, Pyrimidine nucleoside phosphorylase C-terminal domainsearch Aldehyde Oxidoreductase; domain 3search, Pyrimidine Nucleoside Phosphorylase; Chain A, domain 2search, Transferase, Pyrimidine Nucleoside Phosphorylase; Chain Csearch PF00591: Glycosyl transferase family, a/b domainsearch, PF02885: Glycosyl transferase family, helical bundle domainsearch, PF07831: Pyrimidine nucleoside phosphorylase C-terminal domainsearch

Chain ID Molecular function (GO) Biological process (GO)
A, B (P77836) metal ion bindingsearch transferase activity, transferring pentosyl groupssearch pyrimidine-nucleoside phosphorylase activitysearch phosphorylase activitysearch transferase activity, transferring glycosyl groupssearch transferase activitysearch pyrimidine nucleobase metabolic processsearch metabolic processsearch pyrimidine nucleoside metabolic processsearch

Chain InterPro annotation
A, B Pyrimidine-nucleoside phosphorylasesearch Glycosyl transferase, family 3search Pyrimidine nucleoside phosphorylase, C-terminalsearch Glycosyl transferase family 3, N-terminal domainsearch Pyrimidine-nucleoside phosphorylase, conserved sitesearch Pyrimidine-nucleoside phosphorylase, bacterial/eukaryoticsearch