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PDBe Entry: 1brc
RELOCATING A NEGATIVE CHARGE IN THE BINDING POCKET OF TRYPSIN
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| Summary |  |
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| Header |
COMPLEX(PROTEINASE/INHIBITOR)
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| Method | X-RAY DIFFRACTION | |||||||||||||||||||
| Experiment | Resolution: 2.5 Å, R-factor: 16.8%, Spacegroup: P 32 2 1 | |||||||||||||||||||
| Released | 31/05/1994, deposition: 17/12/1992, last revision: 24/02/2009 | |||||||||||||||||||
| Authors |
Perona, J.J.; Fletterick, R.J.
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| Primary citation |
Relocating a negative charge in the binding pocket of trypsin. J.MOL.BIOL. vol:230, pag:934-949 (1993) [PubMed ID 8478942 ]
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| Keywords |
COMPLEX(PROTEINASE/INHIBITOR)
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| EC |
3.4.21.4 ExPASy BRENDA (E)
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| Organism |
Rattus norvegicus(Norway rat) 10116(E)
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| UniProt |
Anionic trypsin-2 precursor (EC 3.4.21.4) (Anionic trypsin II) (Pretrypsinogen II) (Serine protease 2) P00763 (E) Amyloid beta A4 protein precursor (Alzheimer disease amyloid protein) (ABPP) (APPI) (APP) (PreA4) (Cerebral vascular amyloid peptide) (CVAP) (Protease nexin-II) (PN-II) [Contains: Soluble APP-alpha (S-APP-alpha); Soluble APP-beta (S-APP-beta); C99; Beta-amyloid protein 42 (Beta-APP42); Beta-amyloid protein 40 (Beta-APP40); C83; P3(42); P3(40); Gamma-CTF(59) (Gamma-secretase C-terminal fragment 59) (Amyloid intracellular domain 59) (AICD-59) (AID(59)); Gamma-CTF(57) (Gamma-secretase C-terminal fragment 57) (Amyloid intracellular domain 57) (AICD-57) (AID(57)); Gamma-CTF(50) (Gamma-secretase C-terminal fragment 50) (Amyloid intracellular domain 50) (AICD-50) (AID(50)); C31] P05067 (I)
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| Solvent | E, I | |||||||||||||||||||
| Polymers |
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