1bnd Summary

pdbe.org/1bnd
spacer

STRUCTURE OF THE BRAIN-DERIVED NEUROTROPHIC FACTOR(SLASH)NEUROTROPHIN 3 HETERODIMER

The structure was published by Robinson, R.C., Radziejewski, C., Stuart, D.I., and Jones, E.Y., in 1995 in a paper entitled "Structure of the brain-derived neurotrophic factor/neurotrophin 3 heterodimer." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 2.3 Å and deposited in 1994.

The experimental data on which the structure is based was not deposited.

This PDB entry contains a complex of 2 biomacromolecules, namely BRAIN DERIVED NEUROTROPHIC FACTOR and NEUROTROPHIN 3.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule has more than one probable quaternary state observed. For more details see the quaternary structure page.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A BRAIN DERIVED NEUROTROPHIC FACTOR P23560 (129-247) (BDNF_HUMAN)search Homo sapienssearch < 90% 119 91%
B NEUROTROPHIN 3 P20783 (139-257) (NTF3_HUMAN)search Homo sapienssearch < 90% 119 90%


This entry contains 2 unique UniProt proteins:

UniProt accession Name Organism PDB
P23560 (129 - 247) BRAIN DERIVED NEUROTROPHIC FACTOR Homo sapiens
P20783 (139 - 257) NEUROTROPHIN 3 Homo sapiens

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A Neurotrophinsearch Cystine-knot cytokinessearch Nerve growth factor familysearch
B Neurotrophinsearch Cystine-knot cytokinessearch Nerve growth factor familysearch

Chain ID Molecular function (GO)
A (P23560) receptor bindingsearch
B (P20783) neurotrophin receptor bindingsearch receptor bindingsearch

Chain InterPro annotation
A Nerve growth factor-relatedsearch Nerve growth factor conserved sitesearch Nerve growth factor-likesearch Brain-derived neurotrophic factorsearch
B Nerve growth factor-relatedsearch Neurotrophin-3search Nerve growth factor conserved sitesearch Nerve growth factor-likesearch