Function and Biology Details
Reaction catalysed:
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domains:
Structure analysis Details
Assembly composition:
hetero tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-154867 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Cyclin-dependent kinase 6
Molecule details ›
Chain: A
Length: 326 amino acids
Theoretical weight: 36.99 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
Sequence domains: Protein kinase domain
Structure domains:
Length: 326 amino acids
Theoretical weight: 36.99 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
- Canonical:
Q00534 (Residues: 1-326; Coverage: 100%)
Sequence domains: Protein kinase domain
Structure domains:
Cyclin-dependent kinase inhibitor 2A
Molecule details ›
Chain: B
Length: 156 amino acids
Theoretical weight: 16.56 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Structure domains: Ankyrin repeat-containing domain
Length: 156 amino acids
Theoretical weight: 16.56 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical: P42771 (Residues: 1-156; Coverage: 100%)
Structure domains: Ankyrin repeat-containing domain
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
CHESS BEAMLINE A1
Spacegroup:
P4122
Expression systems:
- Spodoptera frugiperda
- Escherichia coli
