1bhf Summary

pdbe.org/1bhf
spacer

P56LCK SH2 DOMAIN INHIBITOR COMPLEX

The structure was published by Tong, L., Warren, T.C., Lukas, S., et al., Betageri, R., Proudfoot, J.R., and Jakes, S., in 1998 in a paper entitled "Carboxymethyl-phenylalanine as a replacement for phosphotyrosine in SH2 domain binding." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 1.8 Å and deposited in 1998.

The experimental data on which the structure is based was not deposited.

This PDB entry contains a complex of 2 biomacromolecules, namely T-LYMPHOCYTE-SPECIFIC PROTEIN TYROSINE KINASE P56LCK and INHIBITOR ACE-IPA-GLU-GLU-ILE.

The molecule most likely forms heterodimers.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A T-LYMPHOCYTE-SPECIFIC PROTEIN TYROSINE KINASE P56LCK P06239 (119-226) (LCK_HUMAN)search Homo sapienssearch < 90% 108 97%


This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P06239 (119 - 226) T-LYMPHOCYTE-SPECIFIC PROTEIN TYROSINE KINASE P56LCK Homo sapiens

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A SH2 domainsearch SHC Adaptor Proteinsearch SH2 domainsearch
Chain InterPro annotation
A SH2 domainsearch