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A326S MUTANT OF AN INHIBITORY ALPHA SUBUNIT

Source organism: Rattus norvegicus
Biochemical function: G-protein beta/gamma-subunit complex binding
Biological process: adenylate cyclase-modulating G protein-coupled receptor signaling pathway
Cellular component: not assigned

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GO terms

Sequence family

Pfam Protein family (Pfam)
PF00503
Domain description: G-protein alpha subunit
Occurring in:
  1. Guanine nucleotide-binding protein G(i) subunit alpha-1
The deposited structure of PDB entry 1bh2 contains 1 copy of Pfam domain PF00503 (G-protein alpha subunit) in Guanine nucleotide-binding protein G(i) subunit alpha-1. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR001019
Domain description: Guanine nucleotide binding protein (G-protein), alpha subunit
Occurring in:
  1. Guanine nucleotide-binding protein G(i) subunit alpha-1
IPR001408
Domain description: G-protein alpha subunit, group I
Occurring in:
  1. Guanine nucleotide-binding protein G(i) subunit alpha-1
IPR011025
Domain description: G protein alpha subunit, helical insertion
Occurring in:
  1. Guanine nucleotide-binding protein G(i) subunit alpha-1
IPR027417
Domain description: P-loop containing nucleoside triphosphate hydrolase
Occurring in:
  1. Guanine nucleotide-binding protein G(i) subunit alpha-1

Structure domains

CATH CATH domains
3.40.50.300
Class: Alpha Beta
Architecture: 3-Layer(aba) Sandwich
Topology: Rossmann fold
Homology: P-loop containing nucleotide triphosphate hydrolases
Occurring in:
  1. Guanine nucleotide-binding protein G(i) subunit alpha-1
The deposited structure of PDB entry 1bh2 contains 1 copy of CATH domain 3.40.50.300 (Rossmann fold) in Guanine nucleotide-binding protein G(i) subunit alpha-1. Showing 1 copy in chain A.
1.10.400.10
Class: Mainly Alpha
Architecture: Orthogonal Bundle
Topology: GI Alpha 1, domain 2-like
Homology: GI Alpha 1, domain 2-like
Occurring in:
  1. Guanine nucleotide-binding protein G(i) subunit alpha-1
The deposited structure of PDB entry 1bh2 contains 1 copy of CATH domain 1.10.400.10 (GI Alpha 1, domain 2-like) in Guanine nucleotide-binding protein G(i) subunit alpha-1. Showing 1 copy in chain A.
SCOP SCOP annotations
52592
Class: Alpha and beta proteins (a/b)
Fold: P-loop containing nucleoside triphosphate hydrolases
Superfamily: P-loop containing nucleoside triphosphate hydrolases
Occurring in:
  1. Guanine nucleotide-binding protein G(i) subunit alpha-1
The deposited structure of PDB entry 1bh2 contains 1 copy of SCOP domain 52592 (G proteins) in Guanine nucleotide-binding protein G(i) subunit alpha-1. Showing 1 copy in chain A.
47896
Class: All alpha proteins
Fold: Transducin (alpha subunit), insertion domain
Superfamily: Transducin (alpha subunit), insertion domain
Occurring in:
  1. Guanine nucleotide-binding protein G(i) subunit alpha-1
The deposited structure of PDB entry 1bh2 contains 1 copy of SCOP domain 47896 (Transducin (alpha subunit), insertion domain) in Guanine nucleotide-binding protein G(i) subunit alpha-1. Showing 1 copy in chain A.

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