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PDBe Entry: 1bgo 
CRYSTAL STRUCTURE OF CYSTEINE PROTEASE HUMAN CATHEPSIN K IN COMPLEX WITH A COVALENT PEPTIDOMIMETIC INHIBITOR
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HYDROLASE
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X-RAY DIFFRACTION
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Resolution: 2.3 Å, R-factor: 24.0%, Free R-factor: 29.6%, Spacegroup: P 43
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08/06/1999, deposition: 29/05/1998, last revision: 24/02/2009
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Desjarlais, R.L.; Yamashita, D.S.; Oh, H.-J.; Bondinell, W.E.; Uzinskas, I.N.; Erhard, K.F.; Allen, A.C.; Haltiwanger, R.C.; Zhao, B.; Smith, W.W.; Abdel-Meguid, S.S.; D'Alessio, K.; Janson, C.A.; Mcqueney, M.S.; Tomaszek, T.A.; Levy, M.A.; Veber, D.F.
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Use of X-Ray Co-Crystal Structures and Molecular Modeling to Design Potent and Selective Non-Peptide Inhibitors of Cathepsin K
J.AM.CHEM.SOC. vol:120, pag:9114 (1998)
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HYDROLASE, SULFHYDRYL PROTEINASE, THIOL PROTEASE
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3.4.22.38 ExPASy BRENDA (A)
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Homo sapiens(human) 9606(A)
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Cathepsin K precursor (EC 3.4.22.38) (Cathepsin O) (Cathepsin X) (Cathepsin O2) P43235 (A)
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A
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| A |
CATHEPSIN K |
Protein |
P43235 (CATK_HUMAN)
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215 |
100% |
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| A |
1-[2-(3-BIPHENYL)-4-METHYLVALERYL)]AMINO-3-(2-PYRIDYLSULFONYL)AMINO-2-PROPANONE |
I10
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