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PDBe Entry: 1bdl 
HIV-1 (2:31-37) PROTEASE COMPLEXED WITH INHIBITOR SB203386
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HYDROLASE
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X-RAY DIFFRACTION
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Resolution: 2.8 Å, R-factor: 20.1%, Free R-factor: 25.5%, Spacegroup: P 61
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12/08/1998, deposition: 10/05/1998, last revision: 24/02/2009
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Swairjo, M.A.; Abdel-Meguid, S.S.
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Structural role of the 30's loop in determining the ligand specificity of the human immunodeficiency virus protease.
BIOCHEMISTRY vol:37, pag:10928-10936 (1998) [PubMed ID 9692985 ]
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HYDROLASE, AIDS, POLYPROTEIN, ASPARTYL PROTEASE, ACID PROTEASE, HYDROXYETHYLENE ISOSTERE INHIBITOR, SUBSTRATE ANALOGUE INHIBITOR
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2.7.7.49 ExPASy BRENDA 2.7.7.7 ExPASy BRENDA 3.1.26.4 ExPASy BRENDA 3.4.23.16 ExPASy BRENDA (A B)
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Human immunodeficiency virus 1 11676(A B)
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Gag-Pol polyprotein (Pr160Gag-Pol) [Contains: Matrix protein p17 (MA); Capsid protein p24 (CA); Spacer peptide p2; Nucleocapsid protein p7 (NC); Transframe peptide (TF); p6-pol (p6*); Protease (EC 3.4.23.16) (Retropepsin) (PR); Reverse transcriptase/ribonuclease H (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4) (p66 RT); p51 RT; p15; Integrase (IN)] P04587 (A B)
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A, B
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| A, B |
HIV-1 PROTEASE |
Protein |
P04587 (POL_HV1B5)
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99 |
100% |
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| A, B |
(2R,4S,5S,1'S)-2-PHENYLMETHYL-4-HYDROXY-5-(TERT-BUTOXYCARBONYL)AMINO-6-PHENYL HEXANOYL-N-(1'-IMIDAZO-2-YL)-2'-METHYLPROPANAMIDE |
IM1
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