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COMPLEX STRUCTURE OF HPT DOMAIN AND CHEY

Source organism: Escherichia coli
Biochemical function: metal ion binding
Biological process: phosphorelay signal transduction system
Cellular component: bacterial-type flagellum rotor complex

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EC 2.7.13.3: Histidine kinase

Reaction catalysed:
ATP + protein L-histidine = ADP + protein N-phospho-L-histidine
Systematic name:
ATP:protein-L-histidine N-phosphotransferase
Alternative Name(s):
  • EnvZ
  • HK1
  • HP165
  • Histidine protein kinase
  • Protein histidine kinase
  • Protein kinase
  • Protein kinase (histidine)
  • Sln1p

GO terms

Sequence families

Pfam Protein families (Pfam)
PF01627
Domain description: Hpt domain
Occurring in:
  1. Aerobic respiration control sensor protein ArcB
The deposited structure of PDB entry 1bdj contains 1 copy of Pfam domain PF01627 (Hpt domain) in Aerobic respiration control sensor protein ArcB. Showing 1 copy in chain B.

PF00072
Domain description: Response regulator receiver domain
Occurring in:
  1. Chemotaxis protein CheY
The deposited structure of PDB entry 1bdj contains 1 copy of Pfam domain PF00072 (Response regulator receiver domain) in Chemotaxis protein CheY. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR008207
Domain description: Signal transduction histidine kinase, phosphotransfer (Hpt) domain
Occurring in:
  1. Aerobic respiration control sensor protein ArcB
IPR001789
Domain description: Signal transduction response regulator, receiver domain
Occurring in:
  1. Chemotaxis protein CheY
IPR036641
Domain description: HPT domain superfamily
Occurring in:
  1. Aerobic respiration control sensor protein ArcB
IPR011006
Domain description: CheY-like superfamily
Occurring in:
  1. Chemotaxis protein CheY

Structure domains

CATH CATH domains
1.20.120.160
Class: Mainly Alpha
Architecture: Up-down Bundle
Topology: Four Helix Bundle (Hemerythrin (Met), subunit A)
Homology: HPT domain
Occurring in:
  1. Aerobic respiration control sensor protein ArcB
The deposited structure of PDB entry 1bdj contains 1 copy of CATH domain 1.20.120.160 (Four Helix Bundle (Hemerythrin (Met), subunit A)) in Aerobic respiration control sensor protein ArcB. Showing 1 copy in chain B.
3.40.50.2300
Class: Alpha Beta
Architecture: 3-Layer(aba) Sandwich
Topology: Rossmann fold
Homology: Rossmann fold
Occurring in:
  1. Chemotaxis protein CheY
The deposited structure of PDB entry 1bdj contains 1 copy of CATH domain 3.40.50.2300 (Rossmann fold) in Chemotaxis protein CheY. Showing 1 copy in chain A.
SCOP SCOP annotations
47227
Class: All alpha proteins
Fold: Four-helical up-and-down bundle
Superfamily: Histidine-containing phosphotransfer domain, HPT domain
Occurring in:
  1. Aerobic respiration control sensor protein ArcB
The deposited structure of PDB entry 1bdj contains 1 copy of SCOP domain 47227 (Aerobic respiration control sensor protein, ArcB) in Aerobic respiration control sensor protein ArcB. Showing 1 copy in chain B.
52173
Class: Alpha and beta proteins (a/b)
Fold: Flavodoxin-like
Superfamily: CheY-like
Occurring in:
  1. Chemotaxis protein CheY
The deposited structure of PDB entry 1bdj contains 1 copy of SCOP domain 52173 (CheY-related) in Chemotaxis protein CheY. Showing 1 copy in chain A.

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