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PDBe Entry: 1bck view

HUMAN CYCLOPHILIN A COMPLEXED WITH 2-THR CYCLOSPORIN
Summary
Header COMPLEX (ISOMERASE/IMMUNOSUPPRESSANT)search
Method X-RAY DIFFRACTION
Experiment Resolution: 1.8 Å, R-factor: 18.6%, Spacegroup: P 21 21 21
Released 16/09/1998, deposition: 30/04/1998, last revision: 24/02/2009
Authors Mikol, V.search; Kallen, J.search; Taylor, P.search; Walkinshaw, M.D.search
Primary citation X-ray structures and analysis of 11 cyclosporin derivatives complexed with cyclophilin A.
J.MOL.BIOL.search vol:283, pag:435-449 (1998) [PubMed ID 9769216 ]search
Keywords COMPLEX (ISOMERASE/IMMUNOSUPPRESSANT)search
EC 5.2.1.8 ExPASy BRENDA search (A)
Organism Homo sapiens(human) 9606search(A)
UniProt Peptidyl-prolyl cis-trans isomerase A (EC 5.2.1.8) (PPIase A) (Rotamase A) (Cyclophilin A) (Cyclosporin A-binding protein) P62937search (A)
Solvent A, C
Polymers
Id Name Type UniProt Residues Observed
A CYCLOPHILIN A Protein P62937 (PPIA_HUMAN)search
165 100%
C CYCLOSPORIN A Protein
11 100%
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