1ba3 Summary

pdbe.org/1ba3
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FIREFLY LUCIFERASE IN COMPLEX WITH BROMOFORM

The structure was published by Franks, N.P., Jenkins, A., Conti, E., Lieb, W.R., and Brick, P., in 1998 in a paper entitled "Structural basis for the inhibition of firefly luciferase by a general anesthetic." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 2.2 Å and deposited in 1998.

The experimental data on which the structure is based was also deposited.

The PDB entry contains the structure of LUCIFERASE. This molecule has the UniProt identifier P08659 (LUCI_PHOPY)search. The sample contained 550 residues which is 100% of the natural sequence. Out of 550 residues 530 were observed and are deposited in the PDB.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule is most likely monomeric.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A LUCIFERASE P08659 (1-550) (LUCI_PHOPY)search Photinus pyralissearch 100% 550 98%


This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P08659 (1 - 550) LUCIFERASE Photinus pyralis

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A (P08659) Acetyl-CoA synthetase-likesearch Rossmann foldsearch, Luciferase; Domain 3search, GMP Synthetase; Chain A, domain 3search, Luciferase; Domain 5search PF00501: AMP-binding enzymesearch, PF13193: AMP-binding enzyme C-terminal domainsearch

Chain ID Molecular function (GO) Biological process (GO) Cellular component (GO)
A (P08659) monooxygenase activitysearch metal ion bindingsearch oxidoreductase activitysearch catalytic activitysearch Photinus-luciferin 4-monooxygenase (ATP-hydrolyzing) activitysearch nucleotide bindingsearch ATP bindingsearch bioluminescencesearch metabolic processsearch oxidation-reduction processsearch peroxisomesearch

Chain InterPro annotation
A AMP-dependent synthetase/ligasesearch AMP-binding, conserved sitesearch AMP-binding enzyme C-terminal domainsearch Luciferase, N-terminal domainsearch