1b7t Summary



The structure was published by Houdusse, A., Kalabokis, V.N., Himmel, D., Szent-Gyorgyi, A.G., and Cohen, C., in 1999 in a paper entitled "Atomic structure of scallop myosin subfragment S1 complexed with MgADP: a novel conformation of the myosin head." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 2.5 Å and deposited in 1999.

The experimental data on which the structure is based was not deposited.

This PDB entry contains a complex of 3 biomacromolecules, namely MYOSIN HEAVY CHAIN, MYOSIN REGULATORY LIGHT CHAIN, and MYOSIN ESSENTIAL LIGHT CHAIN.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule most likely forms heterotrimers.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):

Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A MYOSIN HEAVY CHAIN P24733 (1-835) (MYS_ARGIR)search Argopecten irradianssearch < 90% 835 91%
Y MYOSIN REGULATORY LIGHT CHAIN P13543 (2-157) (MLR_ARGIR)search Argopecten irradianssearch 92% 156 88%
Z MYOSIN ESSENTIAL LIGHT CHAIN P07291 (2-157) (MLE_ARGIR)search Argopecten irradianssearch 95% 156 98%

This entry contains 3 unique UniProt proteins:

UniProt accession Name Organism PDB
P24733 (1 - 835) MYOSIN HEAVY CHAIN Argopecten irradians
P13543 (2 - 157) MYOSIN REGULATORY LIGHT CHAIN Argopecten irradians
P07291 (2 - 157) MYOSIN ESSENTIAL LIGHT CHAIN Argopecten irradians

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A Myosin S1 fragment, N-terminal domainsearch, Motor proteinssearch Myosin head (motor domain)search, IQ calmodulin-binding motifsearch, Myosin N-terminal SH3-like domainsearch
Y (P13543) Calmodulin-likesearch EF-handsearch PF00036: EF handsearch
Z (P07291) Calmodulin-likesearch EF-handsearch

Chain ID Molecular function (GO) Cellular component (GO)
A (P24733) ATP bindingsearch motor activitysearch myosin complexsearch
Y (P13543) calcium ion bindingsearch metal ion bindingsearch myosin complexsearch
Z (P07291) calcium ion bindingsearch myosin complexsearch

Chain InterPro annotation
A IQ motif, EF-hand binding sitesearch Myosin head, motor domainsearch Myosin, N-terminal, SH3-likesearch Myosin-like IQ motif-containing domainsearch P-loop containing nucleoside triphosphate hydrolasesearch
Y EF-hand domainsearch EF-hand domain pairsearch EF-Hand 1, calcium-binding sitesearch
Z EF-hand domainsearch EF-hand domain pairsearch