1b66 Summary

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6-PYRUVOYL TETRAHYDROPTERIN SYNTHASE

The structure was published by Ploom, T., Thony, B., Yim, J., et al., Richardson, J., Huber, R., and Auerbach, G., in 1999 in a paper entitled "Crystallographic and kinetic investigations on the mechanism of 6-pyruvoyl tetrahydropterin synthase." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 1.9 Å and deposited in 1999.

The experimental data on which the structure is based was not deposited.

This PDB entry contains multiple copies of the structure of 6-PYRUVOYL TETRAHYDROPTERIN SYNTHASE.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule has more than one probable quaternary state observed. For more details see the quaternary structure page.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A 6-PYRUVOYL TETRAHYDROPTERIN SYNTHASE P27213 (5-144) (PTPS_RAT)search Rattus norvegicussearch 97% 140 98%
B 6-PYRUVOYL TETRAHYDROPTERIN SYNTHASE P27213 (5-144) (PTPS_RAT)search Rattus norvegicussearch 97% 140 98%


This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P27213 (5 - 144) 6-PYRUVOYL TETRAHYDROPTERIN SYNTHASE Rattus rattus

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A, B (P27213) 6-pyruvoyl tetrahydropterin synthasesearch Tetrahydropterin Synthase; Chain Asearch PF01242: 6-pyruvoyl tetrahydropterin synthasesearch

Chain ID Molecular function (GO) Cellular component (GO) Biological process (GO)
A, B (P27213) protein homodimerization activitysearch lyase activitysearch 6-pyruvoyltetrahydropterin synthase activitysearch identical protein bindingsearch metal ion bindingsearch mitochondrionsearch cytoplasmsearch cellular_componentsearch tetrahydrobiopterin biosynthetic processsearch

Chain InterPro annotation
A, B 6-pyruvoyl tetrahydropterin synthase/QueD family proteinsearch 6-pyruvoyl tetrahydropterin synthase, histidine active sitesearch 6-pyruvoyl tetrahydropterin synthase, cysteine active sitesearch