1b4c Summary

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SOLUTION STRUCTURE OF RAT APO-S100B USING DIPOLAR COUPLINGS

The structure was published by Drohat, A.C., Tjandra, N., Baldisseri, D.M., and Weber, D.J., in 1999 in a paper entitled "The use of dipolar couplings for determining the solution structure of rat apo-S100B(betabeta)." (abstract).

The structure was determined using NMR spectroscopy and deposited in 1998.

The experimental data on which the structure is based was also deposited.

This PDB entry contains multiple copies of the structure of PROTEIN (S-100 PROTEIN, BETA CHAIN).

The molecule most likely forms homodimers.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A PROTEIN (S-100 PROTEIN, BETA CHAIN) P04631 (1-92) (S100B_RAT)search Rattus norvegicussearch 99% 92 100%
B PROTEIN (S-100 PROTEIN, BETA CHAIN) P04631 (1-92) (S100B_RAT)search Rattus norvegicussearch 99% 92 100%


This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P04631 (1 - 92) PROTEIN (S-100 PROTEIN, BETA CHAIN) Rattus norvegicus

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A, B (P04631) S100 proteinssearch EF-handsearch PF01023: S-100/ICaBP type calcium binding domainsearch

Chain ID Molecular function (GO) Biological process (GO) Cellular component (GO)
A, B (P04631) calcium ion bindingsearch zinc ion bindingsearch metal ion bindingsearch RAGE receptor bindingsearch protein homodimerization activitysearch receptor bindingsearch protein bindingsearch calcium-dependent protein bindingsearch identical protein bindingsearch S100 protein bindingsearch tau protein bindingsearch response to methylmercurysearch positive regulation of cell proliferationsearch response to glucocorticoidsearch long-term synaptic potentiationsearch learning or memorysearch regulation of cell shapesearch positive regulation of synaptic transmissionsearch memorysearch negative regulation of skeletal muscle cell differentiationsearch astrocyte differentiationsearch regulation of neuronal synaptic plasticitysearch cellular response to hypoxiasearch positive regulation of I-kappaB kinase/NF-kappaB signalingsearch positive regulation of apoptotic processsearch intracellular membrane-bounded organellesearch nucleussearch perinuclear region of cytoplasmsearch neuronal cell bodysearch cytoplasmsearch extracellular spacesearch rufflesearch

Chain InterPro annotation
A, B S100/Calbindin-D9k, conserved sitesearch EF-hand domainsearch EF-hand domain pairsearch S100/CaBP-9k-type, calcium binding, subdomainsearch EF-Hand 1, calcium-binding sitesearch Protein S100-Bsearch