spacer
EBI PDBe PDBeView

PDBe Entry: 1b47 view

STRUCTURE OF THE N-TERMINAL DOMAIN OF CBL IN COMPLEX WITH ITS BINDING SITE IN ZAP-70
Summary
Header SIGNAL TRANSDUCTIONsearch
Method X-RAY DIFFRACTION
Experiment Resolution: 2.2 Å, R-factor: 21.8%, Free R-factor: 26.6%, Spacegroup: C 1 2 1
Released 27/04/1999, deposition: 06/01/1999, last revision: 24/02/2009
Authors Meng, W.search; Sawasdikosol, S.search; Burakoff, S.J.search; Eck, M.J.search
Primary citation Structure of the amino-terminal domain of Cbl complexed to its binding site on ZAP-70 kinase.
NATUREsearch vol:398, pag:84-90 (1999) [PubMed ID 10078535 ]search
Keywords CBLsearch, SIGNAL TRANSDUCTIONsearch, SH2search, PROTO-ONCOGENEsearch
Organism Homo sapiens(human) 9606search(A B C)
UniProt E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto-oncogene) (RING finger protein 55) P22681search (A B C)
Solvent A, B, C
Polymers
Id Name Type UniProt Residues Observed
A, B, C CBL Protein P22681 (CBL_HUMAN)search
 304 100%
Heterogens
Id Name Ligands
A, B, C CALCIUM ION CA search
spacer