1b07 Summary



The structure was published by Nguyen, J.T., Turck, C.W., Cohen, F.E., Zuckermann, R.N., and Lim, W.A., in 1998 in a paper entitled "Exploiting the basis of proline recognition by SH3 and WW domains: design of N-substituted inhibitors." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 2.5 Å and deposited in 1998.

The experimental data on which the structure is based was not deposited.

This PDB entry contains a complex of 2 biomacromolecules, namely PROTEIN (PROTO-ONCOGENE CRK (CRK)) and PROTEIN (SH3 PEPTOID INHIBITOR).

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule most likely forms heterodimers.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):

Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A PROTEIN (PROTO-ONCOGENE CRK (CRK)) Q64010 (134-190) (CRK_MOUSE)search Mus musculussearch < 90% 65 90%
C PROTEIN (SH3 PEPTOID INHIBITOR) Q62245 (1135-1144) (SOS1_MOUSE)search Mus musculussearch < 90% 12 83%

This entry contains 2 unique UniProt proteins:

UniProt accession Name Organism PDB
Q64010 (134 - 190) PROTEIN (PROTO-ONCOGENE CRK (CRK)) Mus musculus
Q62245 (1135 - 1144) PROTEIN (SH3 PEPTOID INHIBITOR)

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A SH3-domainsearch SH3 Domainssearch SH3 domainsearch
Chain InterPro annotation
A SH3 domainsearch