1aww Summary



The structure was published by Hansson, H., Mattsson, P.T., Allard, P., et al., Vihinen, M., Smith, C.I., and Hard, T., in 1998 in a paper entitled "Solution structure of the SH3 domain from Bruton's tyrosine kinase." (abstract).

The structure was determined using NMR spectroscopy and deposited in 1997.

The experimental data on which the structure is based was also deposited.

The PDB entry contains the structure of BRUTON'S TYROSINE KINASE. This molecule has the UniProt identifier Q06187 (BTK_HUMAN)search. The sample contained 67 residues which is < 90% of the natural sequence. Out of 67 residues 67 were observed and are deposited in the PDB.

The molecule is most likely monomeric.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):

Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A BRUTON'S TYROSINE KINASE Q06187 (212-275) (BTK_HUMAN)search Homo sapienssearch < 90% 67 100%

This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
Q06187 (212 - 275) BRUTON'S TYROSINE KINASE Homo sapiens

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A SH3-domainsearch SH3 Domainssearch SH3 domainsearch
Chain InterPro annotation
A SH3 domainsearch Spectrin alpha chain, SH3 domainsearch