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EBI PDBe PDBeView

PDBe Entry: 1avn view

HUMAN CARBONIC ANHYDRASE II COMPLEXED WITH THE HISTAMINE ACTIVATOR
Summary
Header LYASEsearch
Method X-RAY DIFFRACTION
Experiment Resolution: 2.0 Å, R-factor: 15.4%, Spacegroup: P 1 21 1
Released 24/12/1997, deposition: 17/09/1997, last revision: 24/02/2009
Authors Briganti, F.search; Mangani, S.search; Orioli, P.search; Scozzafava, A.search; Vernaglione, G.search; Supuran, C.T.search
Primary citation Carbonic anhydrase activators: X-ray crystallographic and spectroscopic investigations for the interaction of isozymes I and II with histamine.
BIOCHEMISTRYsearch vol:36, pag:10384-10392 (1997) [PubMed ID 9265618 ]search
Keywords LYASEsearch, OXO-ACIDsearch
EC 4.2.1.1 ExPASy BRENDA search (A)
Organism Homo sapiens(human) 9606search(A)
UniProt Carbonic anhydrase 2 (EC 4.2.1.1) (Carbonic anhydrase II) (CA-II) (Carbonate dehydratase II) (Carbonic anhydrase C) (CAC) P00918search (A)
Solvent A
Polymers
Id Name Type UniProt Residues Observed
A CARBONIC ANHYDRASE II Protein P00918 (CAH2_HUMAN)search
 259 99%
Heterogens
Id Name Ligands
A ZINC ION ZN search
A MERCURY (II) ION HG search
A AZIDE ION AZI search
A HISTAMINE HSM search
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