› 1av2

X-ray diffraction
1.4Å resolution

Gramicidin A/CsCl complex, active as a dimer

Released:
DOI: 10.2210/pdb1av2/pdb
PDB entry 1av2 coloured by chain, front view.
PDB entry 1av2 coloured by chain, side view.
PDB entry 1av2 coloured by chain, top view.
Source organism: Brevibacillus brevis
Primary publication:
The conducting form of gramicidin A is a right-handed double-stranded double helix.
Burkhart BM, Li N, Langs DA, Pangborn WA, Duax WL
Proc Natl Acad Sci U S A 95 12950-5 (1998)
PMID: 9789021

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Structure domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-162111 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
GRAMICIDIN A Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 16 amino acids
Theoretical weight: 1.88 KDa
Source organism: Brevibacillus brevis

Ligands and Environments

3 bound ligands:
Ligand CS 7 x CS
Ligand CL 4 x CL
Ligand MOH 9 x MOH
3 modified residues:
Ligand FVA 4 x FVA
Ligand DLE 16 x DLE
Ligand DVA 8 x DVA

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RUH2R
Spacegroup: P212121
Unit cell:
a: 31.06Å b: 31.88Å c: 52.11Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.156 not available 0.186

Quick links

Citations

6 review citations

Structure and function of "metalloantibiotics".
Ming LJ. (2003)
5 more

6 mentions without citation

The conducting form of gramicidin A is a right-handed double-stranded double helix.
Burkhart et al. (1998)
5 more