1auk

X-ray diffraction
2.1Å resolution

Function and Biology Details

Reaction catalysed:
A cerebroside 3-sulfate + H(2)O = a cerebroside + sulfate
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
homo octamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-147295 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (2 distinct):
Arylsulfatase A Chain: A
Molecule details ›
Chain: A
Length: 489 amino acids
Theoretical weight: 51.96 KDa
Source organism: Homo sapiens
Expression system: Mesocricetus auratus
UniProt:
  • Canonical: P15289 (Residues: 19-507; Coverage: 100%)
Gene name: ARSA
Sequence domains:
Structure domains:

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG
1 bound ligand:
1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: SRS BEAMLINE PX9.5
Spacegroup: I422
Unit cell:
a: 132.63Å b: 132.63Å c: 192.06Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.248 0.232 0.273
Expression system: Mesocricetus auratus