Structure analysis

PIT-1 MUTANT/DNA COMPLEX

X-ray diffraction
2.3Å resolution
Source organism: Rattus norvegicus
Assembly composition:
hetero tetramer (preferred)
Entry contents: 1 distinct polypeptide molecule
2 distinct DNA molecules

Assemblies

Assembly 1 (preferred)
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Multimeric state: hetero tetramer
Accessible surface area: 20413.03 Å2
Buried surface area: 9504.22 Å2
Dissociation area: 2,612.45 Å2
Dissociation energy (ΔGdiss): 21.76 kcal/mol
Dissociation entropy (TΔSdiss): 12.39 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-113440

Macromolecules

Chains: A, B
Length: 146 amino acids
Theoretical weight: 17 KDa
Source organism: Rattus norvegicus
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: P10037 (Residues: 128-273; Coverage: 50%)
Gene names: Ghf-1, Pit-1, Pit1, Pou1f1
Pfam:
InterPro:
CATH:
SCOP:

Search similar proteins

Name: CONSENSUS DNA 25-MER
Representative chains: C
Source organism: Rattus norvegicus [10116]
Expression system: Not provided
Length: 25 nucleotides
Theoretical weight: 7.72 KDa

Search similar DNA

Name: DNA (5'-D(*CP*TP*TP*CP*CP*TP*CP*AP*TP*GP*TP*AP*TP*AP*TP*AP*C P*AP*TP*GP*AP*GP* GP*A)-3')
Representative chains: D
Source organism: Rattus norvegicus [10116]
Expression system: Not provided
Length: 24 nucleotides
Theoretical weight: 7.34 KDa

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