1ar1 Summary

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Structure at 2.7 Angstrom Resolution of the Paracoccus Denitrificans two-subunit Cytochrome C Oxidase Complexed with an Antibody Fv Fragment

The structure was published by Ostermeier, C., Harrenga, A., Ermler, U., and Michel, H., in 1997 in a paper entitled "Structure at 2.7 A resolution of the Paracoccus denitrificans two-subunit cytochrome c oxidase complexed with an antibody FV fragment." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 2.7 Å and deposited in 1997.

The experimental data on which the structure is based was not deposited.

This entry contains 24 copies of 4 unique biopolymers (complete list).

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule most likely forms heterotetramers.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A CYTOCHROME C OXIDASE P98002 (1-558) (COX1B_PARDE)search Paracoccus denitrificanssearch 96% 558 94%
B CYTOCHROME C OXIDASE P08306 (1-298) (COX2_PARDE)search Paracoccus denitrificanssearch 94% 298 84%
C ANTIBODY FV FRAGMENT P18525 (20-117) (HVM54_MOUSE)search Mus musculussearch 98% 127 92%
D ANTIBODY FV FRAGMENT P01636 (8-95) (KV5A4_MOUSE)search ,
P01636 (96-108) (KV5A4_MOUSE)search
Mus musculussearch ,
Mus musculussearch
< 90% ,
< 90%
120 90%


This entry contains 4 unique UniProt proteins:

UniProt accession Name Organism PDB
P98002 (1 - 558) CYTOCHROME C OXIDASE Paracoccus denitrificans
P08306 (1 - 298) CYTOCHROME C OXIDASE Paracoccus denitrificans
P18525 (20 - 117) ANTIBODY FV FRAGMENT Mus musculus
P01636 (8 - 95) ANTIBODY FV FRAGMENT Mus musculus

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A (P98002) Cytochrome c oxidase subunit I-likesearch Cytochrome C Oxidase, chain Asearch PF00115: Cytochrome C and Quinol oxidase polypeptide Isearch
B (P08306) Periplasmic domain of cytochrome c oxidase subunit IIsearch, Cytochrome c oxidase subunit II-like, transmembrane regionsearch Cupredoxins - blue copper proteinssearch, Helix Hairpinssearch PF00116: Cytochrome C oxidase subunit II, periplasmic domainsearch, PF02790: Cytochrome C oxidase subunit II, transmembrane domainsearch
C V set domains (antibody variable domain-like)search Immunoglobulinssearch Immunoglobulin V-set domainsearch
D V set domains (antibody variable domain-like)search Immunoglobulinssearch Immunoglobulin V-set domainsearch

Chain ID Biological process (GO) Molecular function (GO) Cellular component (GO)
A (P98002) electron transport chainsearch ion transportsearch oxidation-reduction processsearch proton transportsearch oxidative phosphorylationsearch hydrogen ion transmembrane transportsearch aerobic respirationsearch transportsearch metal ion bindingsearch oxidoreductase activitysearch cytochrome-c oxidase activitysearch iron ion bindingsearch heme bindingsearch copper ion bindingsearch electron carrier activitysearch integral component of membranesearch plasma membranesearch membranesearch respiratory chainsearch
B (P08306) electron transport chainsearch copper ion bindingsearch cytochrome-c oxidase activitysearch oxidoreductase activitysearch membranesearch integral component of membranesearch
C (P18525) antigen bindingsearch

Chain InterPro annotation
A Cytochrome c oxidase subunit Isearch Cytochrome c oxidase, subunit I bacterial typesearch Cytochrome c oxidase, subunit I, copper-binding sitesearch Cytochrome c oxidase, subunit I domainsearch
B Copper centre Cu(A)search Cytochrome c oxidase subunit II C-terminalsearch Cupredoxinsearch Cytochrome C oxidase subunit II, transmembrane domainsearch Cytochrome c oxidase, subunit IIsearch
C search Immunoglobulin-like domainsearch Immunoglobulin V-set domainsearch Immunoglobulin-like foldsearch
D search Immunoglobulin-like domainsearch Immunoglobulin V-set domainsearch Immunoglobulin-like foldsearch