› 1aqz

X-ray diffraction
1.7Å resolution

CRYSTAL STRUCTURE OF A HIGHLY SPECIFIC ASPERGILLUS RIBOTOXIN, RESTRICTOCIN

Released:
DOI: 10.2210/pdb1aqz/pdb
PDB entry 1aqz coloured by chain, front view.
PDB entry 1aqz coloured by chain, side view.
PDB entry 1aqz coloured by chain, top view.
Source organism: Aspergillus restrictus
Primary publication:
Insights into specificity of cleavage and mechanism of cell entry from the crystal structure of the highly specific Aspergillus ribotoxin, restrictocin.
Yang X, Moffat K
Structure 4 837-52 (1996)
PMID: 8805570

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-159252 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ribonuclease mitogillin Chains: A, B
Molecule details ›
Chains: A, B
Length: 149 amino acids
Theoretical weight: 16.89 KDa
Source organism: Aspergillus restrictus
UniProt:
  • Canonical: P67876 (Residues: 28-176; Coverage: 100%)
Gene name: ret
Structure domains: Microbial ribonucleases

Ligands and Environments

1 bound ligand:
Ligand PO4 3 x PO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X26C
Spacegroup: P21
Unit cell:
a: 50.24Å b: 82.16Å c: 38.04Å
α: 90° β: 100.5° γ: 90°
R-values:
R R work R free
0.237 0.237 0.177

Quick links

Citations

6 review citations

Aspergillus fumigatus and aspergillosis.
Latgé JP. (1999)
5 more

12 mentions without citation

Bioinformatics approaches to classifying allergens and predicting cross-reactivity.
Schein et al. (2007)
11 more