1ap7 Summary



The structure was published by Luh, F.Y., Archer, S.J., Domaille, P.J., et al., Brizuela, L., Brenner, S.L., and Laue, E.D., in 1997 in a paper entitled "Structure of the cyclin-dependent kinase inhibitor p19Ink4d." (abstract).

The structure was determined using NMR spectroscopy and deposited in 1997.

The experimental data on which the structure is based was also deposited.

The PDB entry contains the structure of P19-INK4D. This molecule has the UniProt identifier Q60773 (CDN2D_MOUSE)search. The sample contained 168 residues which is 100% of the natural sequence. Out of 168 residues 168 were observed and are deposited in the PDB.

The molecule is most likely monomeric.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):

Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A P19-INK4D Q60773 (1-166) (CDN2D_MOUSE)search Mus musculussearch 100% 168 100%

This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
Q60773 (1 - 166) P19-INK4D Mus musculus

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A (Q60773) Ankyrin repeatsearch Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeatsearch PF12796: Ankyrin repeats (3 copies)search

Chain ID Biological process (GO) Molecular function (GO) Cellular component (GO)
A (Q60773) negative regulation of cell proliferationsearch sensory perception of soundsearch cell cycle arrestsearch response to retinoic acidsearch negative regulation of cell growthsearch negative regulation of phosphorylationsearch autophagic cell deathsearch regulation of cyclin-dependent protein serine/threonine kinase activitysearch negative regulation of cysteine-type endopeptidase activity involved in apoptotic processsearch response to UVsearch negative regulation of intrinsic apoptotic signaling pathway in response to DNA damagesearch negative regulation of protein serine/threonine kinase activitysearch cell cyclesearch G1/S transition of mitotic cell cyclesearch DNA synthesis involved in DNA repairsearch response to vitamin Dsearch cyclin-dependent protein serine/threonine kinase inhibitor activitysearch protein kinase bindingsearch cytoplasmsearch nucleussearch

Chain InterPro annotation
A Ankyrin repeatsearch Ankyrin repeat-containing domainsearch