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THE ALZHEIMER`S DISEASE AMYLOID A4 PEPTIDE (RESIDUES 1-40)

Solution NMR
PDB entry 1aml coloured by chain, ensemble of 20 models, front view.
PDB entry 1aml coloured by chain, ensemble of 20 models, side view.
PDB entry 1aml coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Soluble APP-beta
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Multimeric state: monomeric
PDBe Complex ID: PDB-CPX-138353

Macromolecules

Amyloid-beta protein 40
Chain: A
Length: 40 amino acids
Theoretical weight: 4.34 KDa
Source organism: Homo sapiens
Expression system: unidentified
UniProt:
  • Canonical: P05067 (Residues: 672-711; Coverage: 5%)
Gene names: A4, AD1, APP
Pfam: Beta-amyloid peptide (beta-APP)
InterPro:
CATH: Amyloidogenic glycoprotein, amyloid-beta peptide
SCOP: Amyloid peptides
Amyloid-beta protein 40 in PDB entry 1aml, assembly 1, front view.
Amyloid-beta protein 40 in PDB entry 1aml, assembly 1, side view.
Amyloid-beta protein 40 in PDB entry 1aml, assembly 1, top view.
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