1ak0 Summary



The structure was published by Romier, C., Dominguez, R., Lahm, A., Dahl, O., and Suck, D., in 1998 in a paper entitled "Recognition of single-stranded DNA by nuclease P1: high resolution crystal structures of complexes with substrate analogs." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 1.8 Å and deposited in 1997.

The experimental data on which the structure is based was not deposited.

The PDB entry contains the structure of P1 NUCLEASE. This molecule has the UniProt identifier P24289 (NUP1_PENCI)search. The sample contained 270 residues which is 100% of the natural sequence. Out of 270 residues 264 were observed and are deposited in the PDB.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule is most likely monomeric.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):

Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A P1 NUCLEASE P24289 (1-270) (NUP1_PENCI)search Penicillium citrinumsearch 100% 270 97%

This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P24289 (1 - 270) P1 NUCLEASE Penicillium citrinum

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A (P24289) P1 nucleasesearch P1 Nucleasesearch PF02265: S1/P1 Nucleasesearch

Chain ID Molecular function (GO) Biological process (GO) Cellular component (GO)
A (P24289) metal ion bindingsearch endonuclease activitysearch hydrolase activity, acting on ester bondssearch nucleic acid bindingsearch nuclease activitysearch hydrolase activitysearch DNA catabolic processsearch nucleic acid phosphodiester bond hydrolysissearch extracellular regionsearch

Chain InterPro annotation
A S1/P1 nucleasesearch Phospholipase C/P1 nuclease domainsearch