1aj8 Summary



The structure was published by Russell, R.J., Ferguson, J.M., Hough, D.W., Danson, M.J., and Taylor, G.L., in 1997 in a paper entitled "The crystal structure of citrate synthase from the hyperthermophilic archaeon pyrococcus furiosus at 1.9 A resolution,." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 1.9 Å and deposited in 1997.

The experimental data on which the structure is based was not deposited.

This PDB entry contains multiple copies of the structure of CITRATE SYNTHASE.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule most likely forms homodimers.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):

Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A CITRATE SYNTHASE Q53554 (7-377) (CISY_PYRFU)search Pyrococcus furiosus DSM 3638search 98% 371 100%
B CITRATE SYNTHASE Q53554 (7-377) (CISY_PYRFU)search Pyrococcus furiosus DSM 3638search 98% 371 100%

This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
Q53554 (7 - 377) CITRATE SYNTHASE Pyrococcus furiosus

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A, B (Q53554) Citrate synthasesearch Citrate Synthase, domain 1search, Cytochrome P450-Terp, domain 2search PF00285: Citrate synthasesearch

Chain ID Biological process (GO) Molecular function (GO) Cellular component (GO)
A, B (Q53554) cellular carbohydrate metabolic processsearch tricarboxylic acid cyclesearch metabolic processsearch transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfersearch catalytic activitysearch transferase activitysearch cytoplasmsearch

Chain InterPro annotation
A, B Citrate synthase-likesearch 2-methylcitrate synthase/citrate synthase type Isearch Citrate synthase-like, coresearch Citrate synthase-like, large alpha subdomainsearch Citrate synthase-like, small alpha subdomainsearch Citrate synthase active sitesearch Citrate synthase, bacterial-typesearch