1aj5 Summary



The structure was published by Blanchard, H., Grochulski, P., Li, Y., et al., Davies, P.L., Elce, J.S., and Cygler, M., in 1997 in a paper entitled "Structure of a calpain Ca(2+)-binding domain reveals a novel EF-hand and Ca(2+)-induced conformational changes." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 2.3 Å and deposited in 1997.

The experimental data on which the structure is based was also deposited.

This PDB entry contains multiple copies of the structure of CALPAIN.

The molecule has more than one probable quaternary state observed. For more details see the quaternary structure page.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):

Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A CALPAIN Q64537 (98-270) (CPNS1_RAT)search Rattus norvegicussearch < 90% 173 100%
B CALPAIN Q64537 (98-270) (CPNS1_RAT)search Rattus norvegicussearch < 90% 173 100%

This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
Q64537 (98 - 270) CALPAIN Rattus norvegicus

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A, B Penta-EF-hand proteinssearch EF-handsearch EF handsearch, EF-hand domain pairsearch

Chain ID Molecular function (GO) Biological process (GO)
A, B (Q64537) calcium ion bindingsearch proteolysissearch

Chain InterPro annotation
A, B EF-hand domainsearch EF-hand domain pairsearch EF-Hand 1, calcium-binding sitesearch Calpain small subunit 1search